Dear ones, please take a look at this blog post and consider whether you might be able to help.
It comes to this: a woman who has adopted two children with Downs Syndrome has identified some needs of other people with Down's and we may be able to help her. If you read the post and find you're able to chip in, you'll see that Michelle (who has her own job and kids and crazy life, just as we all do) has made it easy to donate. This mom doesn't have a non-profit org set up yet, but if I didn't believe Michelle's attestation, I wouldn't pass it along.
And an update: the 501c3 application is in process. I'll keep you posted.